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2022-2023 EVENTS



2022 Events

28 Aug - 01 Sep 2022
The International Surgical Week (ISW)
Kuala Lumpur

31 Aug – 2 Sept 2022
Medical Fair Asia
Marina Bay Sands, Singapore

3-9 September
Medical Fair Asia
Digital, Online

9-10 September 2022
World Pediatrics Conference
Bangkok, Thailand

9-10 September 2022
World Heart and Cardiothoracic Surgery Conference
Bangkok, Thailand

19-21 September 2022
23rd SE-Asian Healthcare & Pharma Show
Kuala Lumpur

27-29 September 2022
Smart Healthcare Expo (Health Malaysia)
MITEC

27-29 September 2022
Asia Pandemic Congress
Kuala Lumpur Convention Centre

19-20 September 2022
23nd Global Nursing Education Conference
Brisbane, Australia

30 Sep - 2 Oct 2022
Malaysia International Dental Show (MIDS)
Sunway Pyramid Convention Centre, Subang Jaya, Malaysia

7-9 November 2022
Saudi International MedLab Expo
Riyadh International Convention and Exhibition Center

7-9 November 2022
Saudi International Pharma Expo
Riyadh International Convention and Exhibition Center

11-13 November 2022
Eldercare Exhibition and Conference Asia (ELDEX Asia 2022)
Suntex Singapore Exhibition and Convention Centre

14-15 November 2022
Healthcare Asia Pacific
Osaka, Japan

2023 Events

30 May – 1 June 2023
APHM
KL Convention Centre, Kuala Lumpur

13-15 September 2023
Medical Fair Thailand
BITEC, Bangkok


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Rare but life-threatening: truth about childhood kidney cancer

Kidney cancer accounts for 7% of all childhood cancer, hence making it a rare condition. Kidney cancer occurs when kidney cells begin to grow and divide uncontrollably that it can impair function and lead to tumour formation. It can be a terrifying experience for parents to see their child struggling with this life-threatening illness.

However, according to Malaysia’s Sunway Medical Centre, children with kidney cancer can be successfully treated with the right approach, regaining their health and returning to normal lives.  Knowledge of the subject will result in the best outcome for a child.

While hospitals offer top-notch medical care and treatment, parents can give their children comfort and support.  Sunway Medical Centre in Sunway City advises parents to be aware of the typical symptoms and signs of childhood cancer as well as when to seek medical attention. The private hospital asserted that kids with kidney cancer have a good prognosis because of advancements in medical research and treatment.

Wilms’ tumour

Wilms’ tumour is the most common type of paediatric kidney cancer. They are caused by mutations in kidney cells that typically occur after birth and usually affect one kidney. However, in 5% to 7% of cases, it can be found in both kidneys and the majority of cases are sporadic.

The cause of most cases of childhood cancers unknown. However, there are certain inherent genetic disorders that are present in a child that increases their risk of developing Wilms’ tumour.

It can either occur in isolation such as aniridia (absence of iris in the eye), hemihypertrophy or overgrowth of one side of the body, or as part of a syndrome (a collection of signs and symptoms that occur together).

One of these syndromes is WAGR, which is the acronym for Wilms’ tumour, aniridia, genitourinary malformation, and range of developmental delays. Patients with WAGR syndrome have a 45% to 60% chance of developing Wilms’ tumour.

Dr EniJuraida Abdul Rahman, Consultant Paediatrician and Paediatric Haematologist & Oncologist at Sunway Medical Centre, Sunway City explains, Wilms’ tumour is a cancer that occurs in young children usually under the age of 5 years. “As the child grows older, the risk of them developing Wilms tumour is lesser, and we hardly ever see Wilms’ tumour in adults.”

Watch out for these symptoms

-Painless swelling in the abdomen. Occasionally noted by parents while bathing the child. The tumour may cause the abdomen to swell, causing discomfort

-Haematuria or presence of blood in urine

-Hypertension. Wilms’ tumour can cause high blood pressure

-Fever

-Loss of appetite. Children may experience a loss of appetite, resulting in weight loss

-Pain in the abdomen especially if there is bleeding within the tumour causing a sudden increase in size of the mass

-Generally feeling unwell

-Cough and shortness of breath if the tumour has spread to the lungs

Treatment

According to Dr Eni, in most cases, by the time the child arrives for a diagnosis, the tumour has grown to a large size, and the kidney is effectively non-functional.

If kidney tumour is suspected, the patient will undergo blood tests to look into the general health of the patient, haemoglobin level and kidney function.

Radiological examination is also performed such as an ultrasound of the abdomen, CT scan to further define the tumour, and for staging.

Tumour staging

  1. Tumour is within the kidney
  2. Tumour is still within the kidney but has involved surrounding fatty tissue and blood vessels but can still be completely removed
  • Very large tumours that has crossed the midline of the body
  1. Tumour has spread to distant sites usually the lungs, liver or bone
  2. Tumour involving both kidneys

Subsequently, depending on the stage of the tumour, the patient will undergo:

  • Surgery or nephrectomy to remove the affected kidney. This is usually done upfront for stage I or II tumours or delayed for stage III disease. Surgery is the mainstay of treatment and all children with undergo surgery. What will cure the child is surgery, and not the chemotherapy, Dr Eni explains. All efforts will be futile if the tumour grows back without a follow-up surgery after chemotherapy. Partial nephrectomy or renal-sparing surgery is reserved for bilateral tumours
  • Chemotherapy where drugs are given that will kill the cancer cells. This can be an adjuvant – given after surgery to kill any remaining cancer cells. For stage I and II tumours; and neoadjuvant, which is given before surgery to reduce the size of the tumour and kill cells that have spread to other areas. Chemotherapy is given upfront for stage III tumours because the tumour is very big. The aim is to shrink the tumour to allow surgery to be carried out safely.
  • Radiotherapy in some patients depending on what the tumour looks like microscopically, how far it has spread outside the kidney or if it has spread to distant organs such as the lung and has not completely resolved with chemotherapy

Outcome and prevention

The outcome for Wilms’ tumour is good. “For stage 1 Wilms’ tumour, the cure rate is 95%. Similarly, for stages II to IV, if there are no unfavourable features in the histology, a 4 year survival rate of 90% can be expected,” Dr Eni elaborates. “Since we don’t know the cause, it is difficult to have any preventive measure.However, for children who have abnormalities such as WAGR, surveillance ultrasound of the abdomen are carried out periodically e.g. every six months to detect the occurrence of this tumour. Parents are also counselled to be more vigilant regarding symptoms and signs. It is the hospital’s responsibility to increase public awareness on what are the common symptoms and signs of childhood cancer,” Dr Eni shares.

Though there aren’t any preventive measures, these are things to look out for:

  1. Most tumours are discovered incidentally. It is a good idea to keep an eye out for lumps when parents are dressing or bathing their child. It will be obvious when one side of the stomach looks bigger than the other.
  2. Presence of blood in the urine. This symptom is commonly known as haematuria. This shows that the bleeding could be coming from the kidney, prostate, or bladder.
  3. Loss of appetite and weight. Tumours that arise from the left kidney, will compress the stomach as it grows bigger leading to a sense of fullness when the child eats.
  4. Big birth weights with hemihypertrophy. They have a higher chance of developing a renal tumour. Hence, should be screened periodically.
  5. Advising mothers to exercise caution when taking any health supplements because what we consume is usually metabolised by the liver and some of these substances have been known to affect the function of the liver and the kidney.